Organophosphorus compounds
BIOHIPPO miR-29a-3p-GFP-Puro
miR-29a-3p-GFP-Puro lentiviral vector expressing microRNA 29a with GFP reporter and Puromycin selection for studies in Human/mouse Each vial provides a nominal titer of 1x10E6 transducing units TU miR-29a-3p Lentivirus miRNA lentiviral particles for expression of human/mouse miR-29a (3p) The lentiviral vector contains the entire human miRNA stem-loop which leads to expression of the human/mouse common mature miRNA sequence in transduced cells The miRNA lentivirus is ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation ideal for in vitro or in vivo use and transduction of difficult-to-transfect (e g thawed and/or primary) cells
Medchemexpress LLC mmu-miR-378a-3p inhi 20nmol | 20nmol
mmu-miR-378a-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs The miRNA inhibitors have full-length nucleotide 2 -methoxy modification The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes thereby inhibiting miRNAs from functioning
TARGETMOL CHEMICALS INC BSJ-4-116 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcription primarily through increasing poly(adenylation). purity: 99%
Medchemexpress LLC hsa-miR-140-3p mimic 20nmol | 20nmol
hsa-miR-140-3p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
Medchemexpress LLC Trimethylolpropane ethoxylate triacrylate | 28961-43-5 | 428 | 5 G
Trimethylolpropane ethoxylate triacrylate (ETPTA) is a plasticizer utilized in the synthesis of nanocomposites. It can be used to fabricate photonic crystals with varying stop band positions through photopolymerization of its photocurable resin. Gold nanoparticles can then be embedded into inverse ETPTA films via multiple infiltration.
- Utilized as a plasticizer
- Suitable for synthesizing nanocomposites
- Enables fabrication of photonic crystals
- Supports embedding of gold nanoparticles into films
Medchemexpress LLC hsa-miR-140-3p mimic 5nmol | 5nmol
hsa-miR-140-3p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
![Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.1% | 368.46 g/mol | C18H20N6OS | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000240176.png-250.jpg)
Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.1% | 368.46 g/mol | C18H20N6OS | 1 ML
CYC-116 is a small-molecule inhibitor of Aurora A and Aurora B kinases for laboratory research. It exhibits low-nanomolar affinity (Ki ≈ 8 nM for Aurora A; 9 nM for Aurora B) and is supplied as a high-purity solid or as a 10 mM solution in DMSO for in vitro studies. Intended for research use only.
- Potent Aurora A and B inhibition with Kis of 8 nM and 9 nM.
- High purity (≈99.1%) suitable for biochemical assays.
- Available as solid and 10 mM 1 mL solution in DMSO.
- Molecular formula C18H20N6OS; molecular weight 368.46 g/mol.
- Storage: powder -20°C (up to 3 years); solution -80°C (recommended).
- Intended for in vitro research use only.
ILEX LIFE SCIENCES LLC GELACELL PCLPLGA CELLCROWN 6W
Gelacell - PCL:PLGA scaffolds fixed to cell crowns in 6-well plate for 3D cell culture (1 plate). INTRO: Gelacell, manufactured by Gelatex Technologies, is a unique, 3D microfibrous scaffold specifically engineered for advanced in vitro 3D cell culture and tissue engineering applications. DESCRIPTION: This variant of Gelacell is specially designed for medium-to-long term cell culture durations. Scaffolds made from pharmaceutical grade polycaprolactone + poly lactic-co-glycolic acid (PCL:PLGA ratio is 70:30) are fixed to cell crowns in a 6-well plate. The cell crowns act as Boyden chambers for facilitating studies related to air-liquid interface culture, co-culture, complex tissue models, etc. The optimized design ensures thermal, chemical, and mechanical stability, while also providing substantial swelling capabilities and porosity, allowing efficient nutrient diffusion and thereby preventing cellular waste build up.
![Medchemexpress LLC 1-(3,5-dimethylphenyl)-2-[2-(trifluoromethyl)phenyl]guanidine | 1430208-73-3 | 99.7% | 307.31 g·mol⁻¹ | C16H16F3N3 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241908.png-250.jpg)
Medchemexpress LLC 1-(3,5-dimethylphenyl)-2-[2-(trifluoromethyl)phenyl]guanidine | 1430208-73-3 | 99.7% | 307.31 g·mol⁻¹ | C16H16F3N3 | 25 MG
1A-116 is a small-molecule Rac1 inhibitor that selectively targets the W56 residue to prevent EGF-induced Rac1 activation and disrupt Rac1-P-Rex1 interaction. It induces apoptosis and inhibits cell proliferation, migration, and cell-cycle progression in a concentration-dependent manner, and has demonstrated antimetastatic activity in vivo. Molecular formula C16H16F3N3; molecular weight 307.31 g·mol⁻¹; reported purity 99.72%.
- Selective Rac1 inhibition via W56 targeting.
- Prevents EGF-induced Rac1 activation.
- Blocks Rac1-P-Rex1 interaction.
- Induces apoptosis and inhibits cell proliferation and migration.
- Demonstrates antimetastatic activity in vivo.